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Mifeprin( Mifepristone) Side Effects

Mifeprin( Mifepristone) Side effects Vaginal hemorrhage and uterine spasm are expected consequences of the treatment procedure. Nearly all of the patients who use misoprostol and mifepristone will report undesirable side effects, and numerous patients can be anticipated to report more than one such Mifepristone Side effects. About 90 percent of subjects report undesirable side effects on use of misoprostol on day 3 of the therapy routine.

Mifeprin( Mifepristone) Side effects

Vaginal hemorrhage and uterine spasm are expected consequences of the treatment procedure. Nearly all of the patients who use misoprostol and mifepristone will report undesirable side effects, and numerous patients can be anticipated to report more than one such Mifepristone Side effects. About 90 percent of subjects report undesirable side effects on use of misoprostol on day 3 of the therapy routine.

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Adverse reactions associated with mifepristone use for termination of pregnancy with a frequency-greater than 1% in the trials are abdominal pain, uterine cramping, diarrhoea, dizziness, headache, fatigue, nausea/vomiting and a resultant temporary anorexia, anxiety, asthenia, back pain, chills or rigors, dyspepsia, fever, insomnia, leg pain, leukorrhoea, pelvic pain, sinusitis, syncope or fainting, vaginitis and viral infection, decrease in haemoglobin, uterine haemorrhage, skin rashes and hyperthermia in a few patients. Some adverse events were related to the use of misoprostol with mifepristone on day 3. All of these Mifeprin side effects are relatively common and will usually decrease after day 3and usually disappear after 2 weeks.

In a small number of patients, other complications such as uterine and urinary tract infections have been experienced. These should be treated according to normal clinical practice.

Overdosage:

There are no reports of overdose of mifepristone. In case of over dosage, the patient should be monitored intimately for symptoms of adrenal failure and general supportive measures are recommended.

Dosage and Administration:

Mifepristone (Mifeprin) may be used only in a clinic or hospital, by or under the direction of a doctor who is able to evaluate the gestational period of an embryo and to analyze ectopic pregnancies. Doctors must also be capable to make available surgical intrusion in cases of partial abortion or acute hemorrhage, or have made strategy to endow with such surgical treatment via others, and be able to guarantee subjects contact to medicinal amenities prepared to supply resuscitation and blood transfusions, if obligatory.

Treatment should be initiated with three 200 mg Mifeprin tablets administered in a single dose.

Two days after the initial dose of mifepristone has been administered, the patient should be given two 200 microgram (400mcg) tablets of misoprostol orally.

At some stage in the phase instantly following the use of misoprostol, the subjectt may need drug for spasms or gastrointestinal signs.

Patients should be examined 14 days after this treatment procedure.

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