Hemostan 500mg

 Hemostan 500mg

Tranexamic acid (generally marketed as Hemostan in Asia) is frequently approved for extreme bleeding. Hemostan 500mg is an anti fibrinolytic that effectively thwarts the launch of plasminogen to plasmin, a particle in charge for the dilapidation of fibrin. Fibrin is the fundamental structure for the development of a blood coagulates in hemostasis. It has approximately eight times the anti fibrinolytic action of an older analogue, ε-aminocaproic acid.

Pharmacodynamics

Pharmacokinetics

Tranexamic acid (Hemostan 500mg) is an anti fibrinolytic agent that effectively thwarts breaking of fibrin coagulate. It inhibits joining of plasminogen and plasmin to fibrin, by this means stopping haemostatic plug termination.

Absorption

Riveted from the GI tract; peak plasma absorbtions after three hrs (when administered orally). Bioavailability: 30-50 percent, unaltered by food ingestion.

Distribution

It is broadly distributed all through the human body. Protein-binding: Very low. Transports over the placenta and disseminated into breast milk.

Excretion

Urine (discharged as unlatered drug); two hrs (elimination half-life).

Tranexamic Acid Adverse Reactions

Hemostan Side Effects

Diarrhoea, vomiting, nausea, giddiness, disturbances in color vision, thromboembolic events, hypotension. Consult a doctor in case any of these side effects become persistent and problematic.

These may not be the total possible side effects of Hemostan 500mg, consult your nearest healthcare service provider for further advice.

Precautions

Information Not Available

Special Precautions

Placid to temperate renal injury, uneven menstrual bleeding, haematuria, past recrod of thromboembolic disease. Observe intimately in dispersed intravascular coagulation. Monitor LFT and eye inspection recurrently throughout long-term use. Stop if disorder in color vision takes place. Keep away from IV injection rate less than 1 milliliter per minute due to hazard of hypotension. Pregnancy as well as lactation.

Other Drug Interactions

Information Not Available

Other Interactions

Information Not Available

Food(before/after)

Hemostan 500mg may be used with or without food but advisable to use after food to avoid GI troubles.

Storage

Intravenous

Store at room temperature above 15 degree Celsius and below 30 degree celcisus. Keep away from direct light, heat and moisture.

Oral

Store at room temperature above 15 degree Celsius and below 30 degree celcisus. Keep away from direct light, heat and moisture.

Keep away from the reach of children.